Senneville and Lipsky return with a measured rejoinder in Clinical Infectious Diseases (April 2026), arguing that the Lagrand trial shows the absence of evidence of superiority โ not definitive equivalence โ between ulcer-bed and bone biopsy for guiding antibiotic therapy in diabetic foot osteomyelitis.
Dosing Walking Like a Drug: An AI Chatbot for Diabetic Foot Remission Following Limb Reconstruction #ActAgainstAmputation #DiabeticFoot #Remission #AI #Chatbot @SensorsMDPI @KeckSchool_USC @ALPSLimb @USC_Vascular
A new protocol paper in Sensors describes a chatbot that doses walking like a drug for patients in diabetic foot remission.
The Pressure Is Worth It: Custom Footwear Guided by In-Shoe Pressure Data Is Cost-Effective for Preventing DFU Recurrence #ActAgainstAmputation #DFU #Remission @DiabetologyMdpi @ALPSLimb
A cost-effectiveness analysis of the DIAFOS trial shows that in-shoe plantar pressure-guided custom footwear saves over โฌ8,000 per ulcer prevented โ and adherent patients push the probability of cost-effectiveness to 94%. The economic case for prevention just got stronger.
Control-Alt-Delete: Rebooting the Chronic Wound #ActAgainstAmputation #DFU #WoundHealing @ALPSLimb @KeckSchool_USC @USC_Vascular
Chronic wounds are biological computers stuck in a boot loop. Sharp debridement is Control-Alt-Delete โ the histological reboot that converts a chronic wound back into an acute one. Only then can you run the apps.
One in Three: What the First Year of DFU Remission Really Looks Like #ActAgainstAmputation @DiabetologyMdpi @ALPSLimb @KeckSchool_USC #DFU #Remission #Survivorship
A new systematic review finds that roughly one in three adults in remission after a healed diabetic foot ulcer develop a recurrent ulcer within 12 months โ a risk comparable to several common cancers. Healing is the beginning of the next chapter, not the end of the story.
Prof. David G. Armstrong Delivers Powerful Keynote on Multidisciplinary Care and Digital Health at International Wound Congress in Turkey #ActAgainstAmputation @usc_vascular
FOR IMMEDIATE RELEASE ANTALYA, TURKEY โ David G. Armstrong, DPM, MD, PhD, Distinguished Professor of Surgery and Neurological Surgery at the University of Southern California (USC), has been selected to deliver the opening keynote address at the 19th National & 7th International Wound Congress. The event, held at the Titanic Mardan Palace from December 4โ7,... Continue Reading →
Interpretable Machine Learning to Predict DFU Recurrence #ActAgainstAmputation @alpslimb @KeckSchool_USC @USC_Vascular #AI
I Reflections on new work from the International Flow and Toe Research Team (iFORT) One of the most persistent challenges in limb preservation is not the first ulcer โ it is the next one. Recurrence remains a defining feature of the disease, with up to 60% of people developing a new ulcer within three years... Continue Reading →
What is the Optimal Follow-Up Interval After Diabetic Foot Ulcer Healing in Remission? #ActAgainstAmputation
Our friends and colleagues at the Universidad Complutense de Madridโled by Mateo Lรณpez-Moral, Marta Garcรญa-Madrid, Esther Garcรญa-Morales, Yolanda Garcรญa-รlvarez, Francisco J. รlvaro-Afonso, and Josรฉ Luis Lรกzaro-Martรญnezโhave just published the DIATIME Comparative Efficacy Study, a randomized clinical trial that may help redefine how often we should see patients in remission after a healed diabetic foot ulcerLรณpez-Moral... Continue Reading →
Compromised Skin Barrier at Wound Closure Predicts Recurrence of Diabetic Foot Ulcers: A New TEWL? #ActAgainstAmputation @NIDDKGov #DFC @DiabetesCareADA @ALPSLimb
I An important multicenter study from our colleagues Sen and coworkers and the NIHโs Diabetic Foot Consortium, conducted through the NIDDK Diabetic Foot Consortium, has provided strong evidence that functional closureโnot just structural closureโmatters when it comes to diabetic foot ulcers (DFUs). Published in Diabetes Care, this prospective noninterventional study followed 418 patients with recently... Continue Reading →
When Science Becomes Family: A Conversation on DFU, CLTI, and Recurrence Risk
Itโs not every day that the professional and the personal intersect in such a deeply life-affirming way. Our latest publication in theย International Wound Journal, โThree-Year Recurrence in People With Diabetic Foot Ulcers and Chronic Limb Threatening Ischemia Is Comparable to Cancer,โ brought together an extraordinary team of colleagues from UCSF, Baylor College of Medicine, USC,... Continue Reading →