Novel Glucose-Lowering Agents That Benefit the Diabetic Foot: Icing on the Cake #ActAgainstAmputation

As the global burden of diabetes continues to climb, so too does the impact of its most feared complicationsโ€”including diabetic foot ulcers (DFUs), infections, and amputations. While tight glycemic control has long been a cornerstone of diabetic foot prevention, emerging therapies are now offering benefits that go beyond glucose reduction. In our newly accepted paper... Continue Reading →

Exploring the Risks of SGLT2i vs. DPP-4i as Add-On Therapies in Diabetes Care #Amputation #PAD #CLTI #Stent #DiabetesCare

A new study published in Diabetes Care sheds light on the comparative risks of peripheral artery disease (PAD)-related surgical eventsโ€”such as amputations, stent placements, or vascular surgeriesโ€”between two classes of diabetes medications: sodium-glucose cotransporter 2 inhibitors (SGLT2i) and dipeptidyl peptidase 4 inhibitors (DPP-4i). Conducted among U.S. veterans, this retrospective cohort study analyzed over 150,000 episodes of medication... Continue Reading →

The Potential Impact of SGLT2-I in Diabetic Foot Prevention: Promising Pathophysiologic Implications, State of the Art, and Future Perspectives #WoundHealing #ActAgainstAmputation

A recent review in Medicina highlights the promising role of sodium-glucose cotransporter 2 inhibitors (SGLT2-i) in diabetic foot prevention, presenting a detailed analysis of their physiological impact and potential benefits. Diabetic foot ulcers and related complications remain significant challenges, contributing to high healthcare costs and morbidity. SGLT2-i, originally developed for blood glucose management in diabetes,... Continue Reading →

Up ↑

Verified by MonsterInsights