Wound pH and Surface Temperature as a Predictive Biomarker of Healing in Diabetic Foot Ulcers #Diagnostic #Theragnostic #Thermometry #ActAgainstAmputation @ALPSLIMB

More supportive literature surround inflammation and wound pH Wound pH and Surface Temperature as a Predictive Biomarker of Healing in Diabetic Foot Ulcers - Bhavani Prasad Mahindrakar, Aakansha Giri Goswami, Farhanul Huda, Manisha Naithani, Somprakas Basu, 2023 This graphic from another manuscript (Roychoudhury and coworkers) DOI:10.1149/2.0231808jes Aim To monitor wound pH and surface temperature as... Continue Reading →

Simultaneous Segmentation and Classification of Pressure Injury Image Data Using Mask-R-CNN ActAgainstAmputation #DiabeticFoot @ALPSlimb @USC @USC_vascular @ResearchatUSC @KeckSchool_USC #AI #DeepLearning @TheNPIAP

This just published from our SALSA team led by Mark Swerdlow. We're already getting data requests on this one. Building on these models is what it's all about! Mark Swerdlow,1Ozgur Guler,2Raphael Yaakov,2and David G. Armstrong1 Background. Pressure injuries (PIs) impose a substantial burden on patients, caregivers, and healthcare systems, affecting an estimated 3 million Americans and... Continue Reading →

Smart Wearable Systems for the Remote Monitoring of Selected Vascular Disorders of the Lower Extremity: A Systematic Review #C2SHiP #Wearable #Diagnostic #Theragnostic

A good contribution from Souza and coworkers This systematic review aims at providing an overview of the state of the art regarding smart wearable systems (SWS) applications to monitor the status of patients suffering from vascular disorders of the lower extremity. Peer-reviewed literature has been analyzed to identify employed data collection methods, system characteristics, and... Continue Reading →

Novel Biomarkers for Charcot Foot: A Review of the Literature

An excellent contribution to the literature from Bobirca and coworkers from Bucharest. Abstract Background: Although Charcot diabetic foot (CDF) is a frequent complication of diabetic neuropathy, less is known about the possibility of its early prevention. Methods: A review of the original articles published in English, using the “biomarkers AND Charcot’s foot” criterion, resulted in 33... Continue Reading →

A wound alkalinity measurement to predict non-healing wound outcomes: A literal litmus test #Diagnostics #Theragnostics #WoundHealiing #Diabetic Foot

Again, a literal litmus test to help guide therapy. From Senkowsky and coworkers in JWC More work can be found here and here and here and here (etc). Abstract Objective: As wound pH could influence wound healing rates, this study examined the alkalinity of the entire wound during patients' follow-up visits to predict the final non-healing... Continue Reading →

Association between elevated skin temperature of the foot callus and inflammatory marker in people with diabetes #ActAgainstAmputation #Diagnostic #Theragnostic #DiabeticFoot

Calluses are defined as “hyperkeratosis caused by excessive mechanical loading in particular areas” and can contribute to the development of diabetic foot ulcers(DFUs). Callus inflammation is a premonitory symptom of DFUs. To prevent DFUs, recent studies have recommended thermographic monitoring of foot skin temperature, which is recognized as a sign of skin inflammation. However, no... Continue Reading →

Can Wound Surface pH and Temperature Predict Wound Healing in Diabetic Foot Ulcer? #Theragnostics #Diagnostics #DiabeticFootUlcer

More data supporting diagnostics and theragnostics like wound pH and thermometry. Introduction: Diabetic foot ulcer (DFU) is dreaded and one of the most intricate medical conditions in diabetes. Improving the healing of DFU is imperative for improved patient outcomes. To consider a biomarker of comprehensive value to patients and health care professionals, it should be cost... Continue Reading →

The effect of inflammation management on pH, temperature, and bacterial burden #ActAgainstAmputation #WoundHealing

Important work from Derwin and coworkers in Zena Moore's group. The aim of this feasibility study was to investigate the impact of inflammation management on wound pH, temperature, and bacterial burden, using the principles of TIME and Wound Bed Preparation. A quantitative non-comparative, prospective, descriptive observational design. Following ethical approval, 26 participants with 27 wounds... Continue Reading →

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