Tag: TTT

Another Frontier in Limb Preservation: Automated Periosteal Distraction? #ActAgainstAmputation #WoundHealing

In the journey to eliminate preventable amputations, we continue to look for ways to harness the body’s own regenerative potential. Our latest brief communication describes a significant “first” in the field: the application of fully automated tibial periosteal distraction (PD) for limb preservation. While it has long been understood that applying controlled “tension-stress” to tissue... Continue Reading →

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Further Exploring Tibial Periosteal Distraction as a Adjunct to Healing Diabetic Foot Ulcers

Diabetic foot ulcers (DFUs) represent one of the most significant challenges in managing diabetes-related complications. Affecting millions worldwide, DFUs lead to substantial morbidity, healthcare costs, and a heightened risk of amputation. While traditional therapies like debridement, offloading, and vascular interventions have their place, innovative solutions are crucial to improve outcomes. A recent study by Yuan... Continue Reading →

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Exploring Innovative Limb Salvage Techniques for CLTI – Tibial Cortex Transverse Transport (TTT) and Endovascular intervention

Introduction Chronic limb-threatening ischemia (CLTI) is a severe condition with high risks of amputation and mortality. A groundbreaking study by Ding et al. (2024) has revealed the potential of combining Tibial Cortex Transverse Transport (TTT) with Endovascular Therapy (EVT) to enhance outcomes for patients suffering from CLTI. Key Findings • At 6 months, 85.5% of... Continue Reading →

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Exploring Tibial Cortex Transverse Transport (TTT) for Limb Preservation #ActAgainstAmputation

We are pleased to highlight more initial data with Tibial Cortex Transverse Transport (TTT). This novel approach offers a potential additional intervention for patients with chronic limb-threatening ischemia (CLTI) and severe diabetic foot ulcers (DFUs). The TTT technique, as detailed in a recent case series from our colleagues in Boston, demonstrates the potential for improved... Continue Reading →

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Innovative Periosteal Distraction Technique for Diabetic Foot Ulcer Treatment #ActAgainstAmputation #PeriostealDistraction #PAD #CLTI

Example of sliding plate under skin and periosteum. It is then slowly lifted using (in this case) an external screw A recent study published in the Chinese Journal of Tissue Engineering Research presents an innovative approach for treating diabetic foot ulcers through periosteal distraction. This technique, grounded in Ilizarov's tension-stress principle, promotes both osteogenesis and... Continue Reading →

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Potential Advance in Diabetic Wound Healing? Bone Transport and the Role of Small Extracellular Vesicles #TTT #TibialTransport #ActAgainstAmputation #Mechanism #WoundHealing #DiabeticFoot

More on what I'd like to call "therapeutic distress signals". Like NPWT, which works on skin matrices, could Ilizarov, properly used, stimulate angiogenesis at a distance? Screenshot Screenshot Even more data supporting a potential advance in diabetic wound healing, researchers have uncovered the mechanisms behind bone transport's (BT) effectiveness in treating severe diabetic foot ulcers... Continue Reading →

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What is the induced membrane technique for bone/wound healing and how can it help us #ActAgainstAmputation ?

Induced membrane "Masquelet" technique courtesy of our friend Johnson Boey and colleagues

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Exploring New Frontiers in Diabetic Foot Treatment: The Role of Tibial Cortex Transverse Transport #ActAgainstAmputation

Diabetic foot, a severe complication of diabetes, poses a significant challenge in medical treatment and patient care. Traditional approaches have often focused on managing symptoms and preventing further deterioration, but recent research offers a glimpse into innovative therapeutic strategies that could revolutionize treatment paradigms. Work published on March 19, 2024, in the Journal of Orthopaedic... Continue Reading →

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More on the Potentially Innovative Approach to Neuroischemic Diabetic Foot Ulcers: Modified Tibial Cortex Transverse Transport

Diabetic foot ulcers (DFUs) are a common and severe complication of diabetes, often leading to lower extremity amputations. Traditional treatments, while varied, do not always prevent the progression of these ulcers, particularly in more advanced stages. However, a recent study published by Liu et al. offers hope through a novel surgical technique known as modified... Continue Reading →

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Modified Tibial Cortex Transverse Transport (TTT): Yet more reported data for limb preservation? #ActAgainstAmputation #DiabeticFoot

Diabetic foot ulcers (DFUs) are a significant global health concern, affecting a substantial number of individuals with diabetes. These ulcers often present challenges in achieving healing, leading to prolonged non-healing and, in some cases, necessitating amputation. However, a recent study by Liu et al. (2024) offers a promising new approach to managing DFUs[1]. The Study... Continue Reading →

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