Month: February 2023

Preliminary evaluation of dual-energy CT to quantitatively assess bone marrow edema in patients with diabetic foot ulcers and suspected osteomyelitis

Preliminary evaluation of dual‐energy CT to quantitatively assess bone marrow edema in patients with diabetic foot ulcers and suspected osteomyelitis Great work as usual from our Dutch compatriots Objectives The purpose of this study is to evaluate the value of dual-energy CT (DECT) with virtual non-calcium (VNCa) in quantitatively assessing the presence of bone marrow... Continue Reading →

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Level of 25-hydroxyvitamin D and vitamin D receptor in diabetic foot ulcer and factor associated with diabetic foot ulcers #ActAgainstAmputation @ALPSlimb

Tang and coworkers present these data. Bottom line: The study aimed to investigate the correlation between vitamin D deficiency and diabetic foot osteomyelitis (DFO) in patients with type 2 diabetes mellitus (T2DM) and diabetic foot ulcer (DFU). The levels of serum 25-hydroxyvitamin D [25(OH)VD] and vitamin D receptor (VDR) expression in wound margin tissues were... Continue Reading →

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Wound pH and Surface Temperature as a Predictive Biomarker of Healing in Diabetic Foot Ulcers #Diagnostic #Theragnostic #Thermometry #ActAgainstAmputation @ALPSLIMB

https://www.researchgate.net/publication/325190223_Continuous_Monitoring_of_Wound_Healing_Using_a_Wearable_Enzymatic_Uric_Acid_Biosensor

More supportive literature surround inflammation and wound pH Wound pH and Surface Temperature as a Predictive Biomarker of Healing in Diabetic Foot Ulcers - Bhavani Prasad Mahindrakar, Aakansha Giri Goswami, Farhanul Huda, Manisha Naithani, Somprakas Basu, 2023 This graphic from another manuscript (Roychoudhury and coworkers) DOI:10.1149/2.0231808jes Aim To monitor wound pH and surface temperature as... Continue Reading →

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Sex differences in diabetic foot ulcer severity and outcome #ActAgainstAmputation @ALPSlimb #Belgium @PLoSOne #Location

We thank our Belgian colleagues for this enormously useful data. Bottom line: Sex differences play an important role in the epidemiology, treatment, and outcomes of many diseases. Men with diabetic foot ulcers (DFU) presented with more severe ulcers and had a higher prevalence of previous lower limb revascularization and smoking compared to women. Women with... Continue Reading →

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An novel and alternative treatment method for large heel ulceration in diabetic patients: Proximal tibial cortex transverse distraction #ActAgainstAmputation @ALPSlimb

Callus distraction to heal heel ulcers in type 2 diabetes This work from Jianda and coworkers. There are more and more reports on using this technique to ostensibly improve or augment blood flow in tissue repair. Heel ulceration in patients with diabetes mellitus (DM) is a major clinical challenge, manifesting with a protracted and uncertain... Continue Reading →

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David G. Armstrong Reflects on His Career in Diabetic Foot Care and His Training in Podiatric Surgery ActAgainstAmputation @SamuelMerritU #DiabeticFoot @ALPSlimb @USC @USC_vascular @ResearchatUSC @KeckSchool_USC @podmedcolleges

Here's a wide ranging interview about the value of team and a career in podiatric surgery with USC's Prof. DG. Armstrong. “To see the change happening before our eyes … To see women and men coming up in this field with an interest in limb preservation, an interest to make a difference surgically, medically, mechanically,... Continue Reading →

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Does the skin heat up before it breaks down in diabetic foot ulceration? @ALPSlimb #ActAgainstAmputation

Does the skin heat up before it breaks down in diabetic foot ulceration? Compelling and provocative work from our Dutch colleagues. They've published more on this important subject in the past few years than anyone and what we may be seeing is that, for some patients, thermometry may not be as accurate. While this idea... Continue Reading →

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Accuracy of the pedal acceleration time to diagnose limb ischemia in patients with and without diabetes using the WIfI classification #ActAgainstAmputation @ALPSlimb

Accuracy of the pedal acceleration time to diagnose limb ischemia in patients with and without diabetes using the WIfI classification Excellent work from Castro-Santos and coworkers. Accuracy of the pedal acceleration time to diagnose limb ischemia in patients with and without diabetes using the WIfI classification Introduction: Evaluation of limb hemodynamics using the ankle–brachial index... Continue Reading →

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Outcomes of integrated surgical wound treatment mode based on tibial transverse transport for diabetic foot wound #ActAgainstAmputation @ALPSLimb #DiabeticFoot

Congratulations to Chang and coworkers on this effort. This makes us want to reach back to work from our team a dozen or so years ago, where we failed to really explore this fascinating area of creating, in essence, a distress signal in the bone leading to upregulation of factors that can potentially help toward... Continue Reading →

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American Life in Realtime: a benchmark registry of health data for equitable precision health @USC @ResearchatUSC @KeckSchool_USC @SchaefferCenter @NatureMedicine

This work from our SALSAmiga Ritika Chaturvedi and coworkers is, without question, planting a flag in the ground for precision health and equity. Social, structural and environmental determinants of health, such as food or housing insecurity, systemic racism or chronic stress, account for 60–80% of the modifiable risk of disparities in marginalized populations1,2. Such determinants... Continue Reading →

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