Tang and coworkers present these data.
- The study aimed to investigate the correlation between vitamin D deficiency and diabetic foot osteomyelitis (DFO) in patients with type 2 diabetes mellitus (T2DM) and diabetic foot ulcer (DFU).
- The levels of serum 25-hydroxyvitamin D [25(OH)VD] and vitamin D receptor (VDR) expression in wound margin tissues were found to be significantly lower in patients with DFU and DFO compared to those without DFU or healthy controls.
- Low levels of serum 25(OH)VD and decreased T-VDR expression were identified as independent risk factors for DFU and DFO. Serum 25(OH)VD and T-VDR were also found to be potentially valuable biomarkers for the diagnosis and prognosis of DFU and DFO.
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