Pooled mortality rates following below knee amputation were 33.7%, 51.5%, 53%, 64.4%, and 80% at 1-, 2-, 3-, 5- and 10-year follow-up, respectively

Comprehensive work from Meshkin and coworkers from Georgetown evaluating 36,037 people undergoing major amputation Abstract Chronic wounds that lead to major lower extremity amputation have immense consequences on quality of life, and ultimately, mortality. However, mortality rates after lower extremity amputation for a chronic wound are broad within the literature and have escaped precise definition. […]

Read More Pooled mortality rates following below knee amputation were 33.7%, 51.5%, 53%, 64.4%, and 80% at 1-, 2-, 3-, 5- and 10-year follow-up, respectively

Diagnostic Accuracy of Point-of-Care Fluorescence Imaging for the Detection of Bacterial Burden in Wounds

This excellent work from Le and coworkers strongly suggests that using a point of care diagnostic device (Moleculight) can identify elevated bacterial load and influence medical decision making. Objective: High bacterial load contributes to chronicity of wounds and is diagnosed based on assessment of clinical signs and symptoms (CSS) of infection, but these characteristics are poor […]

Read More Diagnostic Accuracy of Point-of-Care Fluorescence Imaging for the Detection of Bacterial Burden in Wounds

What gait factors cause calluses under the neuropathic foot and what can we do to change it?

This is the thesis behind an interesting gait analysis study from Amemiya and coworkers Bottom line: An effective intervention for preventing callus formation for the first MTH would involve assisting the push-off foot motion using rocker-sole footwear or gait training. For the second and fifth MTHs, wearing appropriate size footwear would be effective.

Read More What gait factors cause calluses under the neuropathic foot and what can we do to change it?

Meta-analysis of the outcomes of metatarsal head resection for the treatment of neuropathic diabetic foot ulcers

This work from Yammine and coworkers. Significance: Diabetic foot ulcers (DFUs) are associated with high morbidity, mortality, and health costs. Standard care (SC) associated with nonsurgical offloading is the mainstay treatment for DFUs, but it has high recurrence and infection rates. Metatarsal head resection (MHR) has been proposed as an effective surgical offloading technique for […]

Read More Meta-analysis of the outcomes of metatarsal head resection for the treatment of neuropathic diabetic foot ulcers

RxForSuccess Podcast- David G. Armstrong: The Storyteller

What a pleasure to participate with master interviewer Dr. Randy Cook in this great visit on the Rxforsuccess podcast. Dr. Armstrong’s Prescription for Success: Number 1: Folks don’t care how much you know, until they know how much you care: Show a sincere interest in the person in front of you, not just their problem.. Number […]

Read More RxForSuccess Podcast- David G. Armstrong: The Storyteller

The Relationship Between Blood Hypoxia-Inducible Factor-1α, Fetuin-A, Fibrinogen, Homocysteine, and Amputation Level

This excellent work from Simsir and coworkers outlines four very important factors that we might want to pay attention to when working on next-gen diagnostics/theragnostics. Reduced life expectancy has resulted from an increased incidence of chronic complications in patients with diabetes. The diabetic foot is one of these complications and generally presents together with diabetic […]

Read More The Relationship Between Blood Hypoxia-Inducible Factor-1α, Fetuin-A, Fibrinogen, Homocysteine, and Amputation Level

Introducing Amazon Halo- The first wearable to measure this feature that we’ve long thought “sounded” helpful…

Early access beta to the Amazon Halo was just released today. It’s a feature rich but very plain (no screen) wearable. It’s most novel feature? Tone. We and others have long been intrigued with using alternative tests to identify stress and emotion. That appears to be what Amazon are going for here… What do you […]

Read More Introducing Amazon Halo- The first wearable to measure this feature that we’ve long thought “sounded” helpful…

Making Sense of Hyperspectral Imaging (and seeing through the dark): Results of A Systematic Review with @KeckMedUSC @IntWoundJournal @USC_Vascular @astar_research @USC

If you’re wondering about the current state of play in hyperspectral and the way forward in making sense of what we’re measuring… Hyperspectral imaging in wound care: A systematic review Abstract Multispectral and hyperspectral imaging (HSI) are emerging imaging tech- niques with the potential to transform the way patients with wounds are cared for, but […]

Read More Making Sense of Hyperspectral Imaging (and seeing through the dark): Results of A Systematic Review with @KeckMedUSC @IntWoundJournal @USC_Vascular @astar_research @USC

Association between race/ethnicity and the risk of amputation of lower extremities among medicare beneficiaries with #diabeticfoot ulcers and diabetic foot infections @BMJ_latest #ActAgainstAmputation

This work from our combined University of Arizona, USC SALSA and University of Washington teams in BMJ Diabetes Introduction This study aimed to examine the association of race and ethnicity on the risk of lower extremity amputations among Medicare beneficiaries with diabetic foot ulcers (DFUs) and diabetic foot infections (DFIs). Research design and methods A retrospective study […]

Read More Association between race/ethnicity and the risk of amputation of lower extremities among medicare beneficiaries with #diabeticfoot ulcers and diabetic foot infections @BMJ_latest #ActAgainstAmputation