Tag: diabetic foot ulcer

Hotspots: Adherence in Home Foot Temperature Monitoring Interventions for At-Risk Feet with Diabetes #ActAgainstAmputation

A recent study published in Diabetic Medicine, titled "Hotspots: Adherence in home foot temperature monitoring interventions for at‐risk feet with diabetes – A narrative review," explores the importance of home foot temperature monitoring (HFTM) for individuals with diabetes who are at risk for foot complications[1]. The study was conducted by our colleague Petra Jones and... Continue Reading →

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Health Literacy predicts incident foot ulcers after 4 years – the SHELLED cohort study #ActAgainstAmputation #DiabeticFoot

This is great work from Pam Chen and coworkers. Aims/hypothesis To determine whether health literacy is associated with an index diabetes-related foot ulcer (DFU). Methods The SHELLED Study is a 4-year prospective study of people with diabetes aged over 40 with no history of DFU. The primary outcome was development of a first foot ulcer.... Continue Reading →

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Concomitant Achilles Tendon Lengthening with Transmetatarsal Amputation for the Prevention of Late Forefoot Ulceration #ActAgainstAmputation #DiabeticFoot #Diabetes

This is an important addition to the literature from the pride of Saginaw, Bullock and coworkers. that is definitely worth a read. It follows on earlier work in JBJS from our team and the team from Washington University, St. Louis. Background: Late development of forefoot ulcers is a common finding after transmetatarsal amputation (TMA). The... Continue Reading →

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One third of people with diabetes will develop diabetic foot complications: Study

Highlights •Lifetime risk of diabetic foot disease (DFD) was 33% in the general population. •Age, glycemic control, diabetes duration, and vascular disease were risk factors. •DFD was associated with amputation, cardiovascular events, major falls, and death. •DFD is a high-risk marker for major morbidity and mortality. This study from our colleagues at Johns Hopkins led... Continue Reading →

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Do diabetes-related foot ulcer wound fluid measures have clinical utility as biomarkers for healing? A systematic review @ALPSlimb #ActAgainstAmputation

This work from Longfield and coworkers from Stephen Twigg's unit further highlight the potential benefit of measuring what we manage. Objective: This study aimed to identify potential biomarkers reported in wound fluid of diabetes-related foot ulcers (DRFUs), and their ability to reflect current and prospective wound healing. Method: A systematic search was executed following the PRISMA methodology... Continue Reading →

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A Wearable Insole System to Measure Plantar Pressure and Shear for People with Diabetes #ActAgainstAmputation @alpslimb #DiabeticFoot

A Wearable Insole System to Measure Plantar Pressure and Shear for People with Diabetes As many know, shear stress has been notoriously difficult to measure in vivo. This is an important step (so to speak) toward addressing that. Great work from our Southampton, Newcastle, and Manchester brethren A Wearable Insole System to Measure Plantar Pressure... Continue Reading →

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‘Smart’ Bandages Monitor Wounds and Provide Targeted Treatment @Caltech @USC ActAgainstAmputation #DiabeticFoot @ALPSlimb @USC_vascular @ResearchatUSC @KeckSchool_USC

This release regarding a manuscript published by our combined Caltech/USC team led by our SALSAmigo, Wei Gao. Also see this from the Guardian newspaper. Summary: A recent study from Caltech and USC reports that smart bandages equipped with biosensors could significantly improve the healing process of chronic wounds. These high-tech bandages monitor wounds in real-time... Continue Reading →

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Unmet needs in diabetes-related foot ulcer (DFU) treatment

Diabetic foot ulcers (DFUs) are a common and severe complication of diabetes, affecting approximately 34% of people with the disease. Despite advancements in treatment, there are still several unmet needs in the care of diabetic foot ulcers that can lead to poor outcomes, including prolonged healing time, infection, hospitalization, and amputation. Some of the key... Continue Reading →

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Three Blinded Adjudicators: Minimizing bias in a diabetic foot ulcer clinical evaluation

This three blinded adjudicator model is one we've been using for several years in recent RCTs. Congrats to our amigos Paul Glat, Lisa Gould, Lael Pickett, and Doug Arm for putting it out there for publication and ultimately iteration. This specific analysis was derived from the HIFLO trial. Summary: The article discusses the steps taken... Continue Reading →

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Mechanisms of diabetic foot ulceration

Mechanisms of diabetic foot ulceration: A review Here's the summary of this manuscript by Deng and coworkers: • Diabetic foot ulcers (DFUs) are a serious complication of diabetes, with complex pathogenic factors. • Previous studies focused on diabetic peripheral vascular disease, neuropathy, and wound infections. • Researchers are now studying immune cells, endothelial cells, keratinocytes,... Continue Reading →

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