Yet more fascinating data in this highly focused area of limb preservation has been published today by Cormier and coworkers in JAPMA. Their data support closing TMAs. Still other works by Lepow and coworkers at our sister institution and our team seem to support open TMA followed by biologic matrix support/NPWT and STSG. What is the right answer? I’m betting that it is far more personalized and based on comorbidities.