The Impact of Diabetic Foot Complications on Mortality in Type 2 Diabetes #ActAgainstAmputation #DiabeticFoot

Unveiling the Link Between Diabetic Foot Complications and Increased Mortality Risk

An important study by Stedman et al. (2023), featured in Diabetes Obesity and Metabolism, sheds light on the often-overlooked impact of diabetic foot complications on mortality rates among individuals with type 2 diabetes (T2D). This study not only quantifies the mortality outcomes linked to foot complications but also investigates how various routinely measured factors can influence this risk.

Understanding the Study’s Approach

The research, conducted from 2010 to 2020, analyzed data from the Salford Integrated Care Record, UK, involving 11,806 T2D patients. The study’s aim was to compare mortality rates and life years lost between those with and without diabetic foot complications.

Startling Findings

  • Elevated Mortality Risk: T2D patients with foot complications exhibited a mortality risk approximately double that of those without such complications.
  • Standardized Mortality Ratio (SMR): The study utilized the Index of Multiple Deprivation-adjusted SMR (SMR_IMD), revealing a startling SMR_IMD of 2.29 for patients with foot complications, compared to 1.13 for those without.
  • Life Years Lost: The impact of foot complications extended to a significant increase in life years lost, underscoring the severity of these complications on overall life expectancy.

The Role of Renal Health

The study highlighted renal health as a pivotal factor in the prognosis of diabetic foot complications. Elevated albumin-to-creatinine ratio and reduced glomerular filtration rate were identified as significant predictors of mortality, emphasizing the need for vigilant renal monitoring in T2D patients.

Implications for Patient Care

  1. Early Detection and Management: Early recognition and management of foot complications can be crucial in reducing mortality risk.
  2. Renal Health Focus: Given the link between renal health and mortality in T2D patients, a dual focus on managing both diabetes and renal health is essential.
  3. Comprehensive Care Strategies: The findings call for a more comprehensive approach to T2D care, integrating routine foot health assessments and renal monitoring.


Stedman et al.’s study provides critical insights into the profound impact of diabetic foot complications on mortality in T2D patients. It underscores the need for a holistic treatment approach, encompassing both diabetes management and vigilant monitoring of renal health, to mitigate these risks and improve patient outcomes.

Reference: Stedman et al. (2023). Diabetes Foot Complications and Standardized Mortality Rate in Type 2 Diabetes. Diabetes Obesity and Metabolism.

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